Freeze-Thawing Effect on Fetal Haemoglobin Conformation and its Interaction with Liposomes
Keywords:
fetal haemoglobin, freeze-thawing, liposomesAbstract
There was studied a freeze-thawing effect on fetal haemoglobin conformation and interaction of its kinetics with phosphatidylcholine- and cardiolipin- formed liposomes. It has been found that freeze-thawing of fetal haemoglobin results in smoothing of temperature-dependent conformational changes in a molecule. Kinetic dependence of fetal haemoglobin and liposomes’ interaction practically does not change after the protein freeze-thawing.
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