Effect of Rat Pretreatment with Embryospecific Factors on the State of Liver Antioxidant System at Hypothermic Storage and Normothermic Reperfusion

Authors

  • D. V. Cherkashina
  • A. Yu. Petrenko

Keywords:

embryospecific factors, liver hypothermic storage, normothermic reperfusion, antioxidant system, free radical damage

Abstract

The effect of embryospecific factor pretreatment on liver oxidative-reducing balance after hypothermic storage (1 and 24 hours) in sucrose-saline solution, and normothermic reperfusion (60 minutes) has been studied. The decrease of free radical product number investigating by TBA-product level and accumulation rate, and normalization of antioxidant system enzyme activity (catalase, glutathione peroxidase and reductase) has been shown.

Author Biographies

D. V. Cherkashina

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

A. Yu. Petrenko

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

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Published

2003-12-25

How to Cite

Cherkashina, D. V., & Petrenko, A. Y. (2003). Effect of Rat Pretreatment with Embryospecific Factors on the State of Liver Antioxidant System at Hypothermic Storage and Normothermic Reperfusion. Problems of Cryobiology and Cryomedicine, (4), 49–57. Retrieved from http://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/1078

Issue

No. 4 (2003): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

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