Use of Modern Cryomethods in Combined Surgical Treatment of Patients with Purulent Chronic Wounds
DOI:
https://doi.org/10.15407/cryo31.02.109Keywords:
purulent wounds, combined surgical treatment, cryopreserved cord blood serum, vacuum therapyAbstract
The paper considers the possibilities of using in medical practice various cryomethods and techniques of cryopreservation of biological objects to treat the patients with purulent chronic wounds (PCW). The variety of methods and approaches to apply cold in medical practice: general and local cryotherapy, cryosurgery etc. has been emphasized. As a result of using each of these methods, regenerative processes begin, which promote the healing of PCW. Particular attention is paid to cryotechniques, ensuring the preservation of cord blood at low temperatures. Cord blood cells and serum have been shown to have immune modulatory and trophic-stimulating therapeutic effects, that is extremely important when treating the patients with PCW. The issue of combined use of cord blood serum and innovative vacuum therapy for the patients with PCW has been considered.
Probl Cryobiol Cryomed 2021; 31(2): 109–115
References
Abdel-Meguid AM, Weshahy AH, Sayed DS, et al. Intralesional vs. contact cryosurgery in treatment of keloids: a clinical and immunohistochemical study. Int J Dermatol. 2015; 54(4): 468- 75. CrossRef
Anatichuk LI, Denisenko OI, Kobylianskiy RR, Kadinuk TY. [About using thermoelectrical cooling in dermatology and cosmetology]. Thermoelectric. 2015; (3): 57-71. Ukranian.
Babaeva AG. [Past, present, and future problems in lymphoid regulation of nonlymphoid cell proliferation]. Biull Eksp Biol Med. 1995 Sep;120(9): 230-4. Russian. CrossRef
Babiychuk VG, Ershova OV, Malysheva GV, et al. Clinical application of rhythmic hypothermia. Problems of Cryobiology. 2002; (1): 85-92.
Eve DJ, Ehrhart J, Zesiewicz T, et al. Plasma derived from human umbilical cord blood modulates mitogen-induced proliferation of mononuclear cells isolated from the peripheral blood of ALS patients. Cell Transplant. 2016; 25(5): 963-71. CrossRef
Gavrilenko AV, Voronov DA. [Results of comprehensive management of patients with chronic lower limb ischaemia using gene-engineering technologies of angiogenesis stimulation (part 1)]. Angiology and vascular surgery. 2015; 21(3): 7-15. Russian.
Gavrilenko AV, Voronov DA. [Results of comprehensive management of patients with chronic lower limb ischaemia using gene-engineering technologies of angiogenesis stimulation (part 2)]. Angiology and vascular surgery. 2015; 21 (4): 29-34. Russian.
Goltsev AN, Yurchenko TN, editors. [Placenta: cryopreservation, clinical use: monograph]. Kharkiv: Brovin AV; 2013. 318 p. Russian.
Goltsev KA, Parkhomenko KIu, Kryvoruchko IA, Shevchenko OM, Azhgybesov KA, Bondarovych MO, Ostankov MV, Goltsev AM. inventors; Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, assignee. [A method of treating acute purulent peritonitis]. Patent of Ukraine N 139447. 2020 Jan 01. Ukrainian.
Goltsev KA, Volina VV, Kozhina OYu, Ostankov MV. Effect of cryopreserved cord blood on structure of immunocompetent and other vital organs at acute pyoperitonitis. Problems of Cryobiology. 2011; 21(4): 429-44. Full Text
Grischenko VI, Prokopyuk OS. Lipina OV. [Procurement, cryopreservation of serum and plasma of cord blood and their clinical use. Methodical recommendations]. Kharkiv; 2000. 11 p. Ukranian.
Grishchenko VI, Goltsev AN. Transplantation of products of embryo-placental complex. From understanding the mechanism of action to improving the effectiveness of the application. Problems of Cryobiology. 2002; (1): 54-84.
Grischenko VI, Krivoruchko IA, Goltsev KA, et al. [Correction of immune impairments by cryopreserved cord blood use during development of acute pyoperitonitis]. Medicine Today and Tomorrow. 2011; (3): 53-62. Russian.
Ischenko IO, Tynynyka LN, Kovaliev GA, et al. [Effect of cryopreserved cord blood serum on biochemical markers of destruction of tissues]. Experimental and clinical medicine. 2016; (1): 19-25. Russian.
Ivanova AA, Antonova AA, Fynageev DM, et al. [Trophic ulcer is a problem of modern surgery]. Youh Scientific Forum: Natural and Medical Sciences. 2017; (5): 93-8. Russian.
Khiao IM, Wallmeyer L, Hedtrich S, et al. The effect of endothelialization on the epidermal differentiation in human three-dimensional skin constructs - a morphological study. Clin Hemorheol Microcirc. 2015;61(2):157-74. CrossRef
Koval AK, Lutsenko ED, Grisha IG, et al. Impact of lyophilisation on integrity of structural and functional characteristics of human cord blood leukoncentrate. Probl Cryobiol Cryomed. 2019; 29 (4): 333-43. CrossRef
Kovalev GA, Vysekantsev IP, Ischenko IO, et al. Effect of cryopreserved cord blood serum and placental extract on cold wound healing. Probl Cryobiol Cryomed. 2015; 25(1): 57-66. CrossRef
Lipina OV, Prokopyuk OS, Savchenko YuA. To the question about cord blood plasm cryopreservation. Problems of Cryobiology. 2000; (4): 83-4.
Olefirenko AA, Tynynyka LN, Sandomirsky BP. Combined usage of cryodestruction and xenoextract to stimulate liver regeneration in rats with experimental cirrhosis. Problems of Cryobiology. 2006; 16(1): 94-100. Full Text
Patel K, Bakshi N, Freehill MT, Awan TM. Whole-body cryotherapy in sports medicine. Curr Sports Med Rep. 2019; 18(4): 136-40. CrossRef
Popovych YaO. Cryopreserved cord blood serum preparation Cryocord-C in treatment of diabetic foot syndrome. Problems of Cryobiology. 2005. 15(1): 63-70. Full Text
Posypenko OB, Stelmakh GO, Bakaluk TG. [Effectiveness of local cryotherapy in treatment of musculoskeletal disorders]. Nursing. 2020; (3): 35-7. Ukranian. CrossRef
Razmakhnin EV, Shangin VA, Kudryavtseva OG, Okhlopkov DY. [Possibilities of vacuum-instillation therapy with dimexidum and betadine in the treatment of purulent wounds]. Acta Biomedica Scientifica (East Siberian Biomedical Journal). 2017;2(6): 153-6. Russian. CrossRef
Sandomirsky BP, Volkova NA. [Skin viability during cryopreservation]. Kyiv: Naukova Dumka; 1985. 87 p. Russian.
Siqueira AF, Vieira A, Ramos GV, et al. Multiple cryotherapy applications attenuate oxidative stress following skeletal muscle injury. Redox Rep. 2017; 22(6): 323-9. CrossRef
Skrzep-Poloczek B, Romuk E, Wisnowiska B, et al. Effect of whole-body cryotherapy on antioxidant systems in experimental rat model. Oxid Med Cell Longev. [Internet]. 2017 Jun 27 [cited 2021 February 12]; 2017;2017:8158702. Available from: https://www.hindawi.com/journals/omcl/2017/8158702/ CrossRef
Sugasawa T, Tome Y, Takeuchi Y, et al. Influence of intermittent cold stimulations on CREB and its targeting genes in muscle: investigations into molecular mechanisms of local cryotherapy. Int J Mol Sci. [Internet]. 2020 Jun 28 [cited 2021 February 12]; 21(13): 4588. Available from: https://www.mdpi.com/1422-0067/21/13/4588 CrossRef
Tettelbach W, Cazzell S, Sigal F, et al. A multicentre prospective randomised controlled comparative parallel study of dehydrated human umbilical cord (EpiCord) allograft for the treatment of diabetic foot ulcers. Int Wound J. 2019; 16(1): 122-30. CrossRef
Vlasov OO, Ishchenko IO, Kovalov GA, et al. Wound repair with cryopreserved cord blood serum treatment In: Proceedings of the Central European conference on regenerative medicine, 2015, March 14-15 Bydgoszcz, Poland. Bydgoszcz; 2015. p. 50-1.
Zembron-Lacny A, Morawin B, Wawrzyniak-Gramacka E, et al. Multiple cryotherapy attenuates oxi-inflammatory response following skeletal muscle injury. Int J Environ Res Public Health. [Internet]. 2020 Oct 27 [cited 2021 February 12]; 17(21): 7855. Available from: https://www.mdpi.com/1660-4601/17/21/7855. CrossRef
Zouboulis CC, Wild T, Zouboulis VA, Har-Shai Y. Intralesional cryosurgery of keloids: required treatment hold time. Br J Dermatol. 2021; 184(1):173-5. CrossRef
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
