Hormone-Producing Ability of Testes Organ Culture in Adult Rats Under Co-culturing and Allotransplantation

Authors

  • A. V. Pakhomov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • G. A. Bozhok Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • E. I. Legach Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

organ culture, testes, adrenal glands, co-transplantation

Abstract

The hormone-producing ability of testes organ culture of adult rats (TOCAR) under co-culturing and allotransplantation with organ culture of adrenal glands of adult rats (OCAGAR) and pituitary explant (PE), was investigated. A decrease in secretory abilities of TOCAR, co-cultured with OCAGAR and PE, was demonstrated. The following co-transplantation of these cultures did not either result in the augmentation of testosterone level in blood of orchiectomized rats. However, the combined allotransplantation of TOCAR and OCAGAR, cultured separately, resulted in a subnormal hormone level recovery in orchiectomized animals.

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Published

2004-09-15

How to Cite

Pakhomov, A. V., Bozhok, G. A., & Legach, E. I. (2004). Hormone-Producing Ability of Testes Organ Culture in Adult Rats Under Co-culturing and Allotransplantation. Problems of Cryobiology and Cryomedicine, (3), 32–38. Retrieved from http://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/672

Issue

Section

Theoretical and Experimental Cryobiology