Embryonic Stem Cell Transplantation

Authors

  • A. V. Karpenko
  • V. N. Bugayev
  • A. I. Smikodub
  • Т. N. Yurchenko

Abstract

The results of long-term clinical investigations of treating patients with diabetes, oncological and hematological diseases using the transplantations of embryonic cellular suspensions are presented: a persistent decrease in the essential daily insulin dose in insulindependent diabetes mellitus, increase in the periods and depth of remission, reduction of compli-cations’ manifestations (anemia, dystrophy,etc); rapid recovery of granulocytes number (3 to 7 days) and blood count in myelotoxic agranulocytoses in oncology and hematology patients, increase in tolerance to chemotherapy, reduction of relapses and metastasising, quality life improvement, a considerable increase in psychoemotional status, decrease in depression component. The sources of stem cells (SCs) are discussed, the unacceptability of material from viable embryos after artificial fertilisation is stated. Legislative and methodological base for the development and coordination of research in the field of embryonic stem cells (ESCs) transplantation is provided.

Author Biographies

A. V. Karpenko

Coordinating Center of Transplantation of Organs, Tissues and Cells of the Ministry of Health Care of Ukraine

V. N. Bugayev

Coordinating Center of Transplantation of Organs, Tissues and Cells of the Ministry of Health Care of Ukraine

A. I. Smikodub

Coordinating Center of Transplantation of Organs, Tissues and Cells of the Ministry of Health Care of Ukraine

Т. N. Yurchenko

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

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Published

2002-09-23

How to Cite

Karpenko, A. V., Bugayev, V. N., Smikodub, A. I., & Yurchenko, Т. N. (2002). Embryonic Stem Cell Transplantation. Problems of Cryobiology and Cryomedicine, (3), 64–72. Retrieved from http://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/962

Issue

No. 3 (2002): Problems of Cryobiology

Section

Cryomedicine, Clinical and Experimental Transplantology

License

Copyright (c) 2020 A. V. Karpenko, V. N. Bugayev, A. I. Smikodub, Т. N. Yurchenko

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