Structural Rearrangements in Cells and Their Membranes Under Long-Term Hypothermic Storage

Authors

  • N. V. Repin
  • T. P. Govorukha

Keywords:

erythrocytes, hepatocytes, hypothermia, ultrastructure

Abstract

Morphological investigation of ultrastructure of erythrocyte membrane and liver cells, stored for a long time under 4°C was carried-out. It was shown, that a manifested destabilisation of their membrane structure, accompanied with spiculae formation and loss of membrane material was observed following 20 days of storage. Ultrastructural state of liver cells after 1 day of storage in a liquid phase testifies to their high integrity and reversibility in the observed changes. By lability extent under hypothermic storage the intracellular structures are graded as follows: mitochondria, endoplasmic reticulum, nuclear apparatus.

Author Biographies

N. V. Repin

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

T. P. Govorukha

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

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Published

2005-12-25

How to Cite

Repin, N. V., & Govorukha, T. P. (2005). Structural Rearrangements in Cells and Their Membranes Under Long-Term Hypothermic Storage. Problems of Cryobiology and Cryomedicine, 15(4), 630–635. Retrieved from https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/1212

Issue

Vol. 15 No. 4 (2005): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

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