Application of Placental Blood Serum to Correct Disordered Morphofunctional State of Adrenal Glands at Experimental Atherosclerosis

Authors

  • Oksana V. Falko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov,
  • Olga S. Prokopyuk Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov,
  • Viktoriya V. Volina Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov,
  • Olga V. Lipina Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov,

Keywords:

atherosclerosis, human placental blood serum, adrenal glands, rabbit, cortisol, cholesterol

Abstract

In the model of experimental atherosclerosis in rabbits there was studied the effect of human placental blood serum on lipid spectrum and morphofunctional state of adrenal glands. It has been shown that placental blood serum contributes to an increase in antiatherogenic fraction of lipoproteids in rabbits blood and recovery of morphological structure of adrenal glands, however does not result in the restoration of functional activity of glands to the mentioned observation terms. Probl Cryobiol Cryomed 2013; 23(1):75–83.

Author Biographies

Oksana V. Falko, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov,

Low Temperature Bank of Biological Objects

Olga S. Prokopyuk, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov,

Low Temperature Bank of Biological Objects

Viktoriya V. Volina, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov,

Low Temperature Bank of Biological Objects

Olga V. Lipina, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov,

Low Temperature Bank of Biological Objects

References

Vasylyuk M.D., Shevchuk S.I., Romanyshyn S.I. et al. Transplantation of cryoplacental tissues in treatment and prevention of diabetic foot. Transplantologiya 2003; 4 (1): 134–135.

Vvedensky B.P., Kovalev G.A., Tynynyka L.N. et al. Cryopreserved cord blood serum during treatment of destructive-dystrophic processes in joints. Vestnik Neotlozhnoy i Vosstanovitelnoy Meditsyny 2012;13 (1): 41–43.

Volkov V.I., Zaprovalnaya O.E., Ladnyy A.I. Correction of thrombic disorders at ischemic heart disease Kyiv: Kniga Plus, 2001.

Glyants E.V. Medical and biological statistics Moscow: Praktika, 1998.

Karpov Yu.A. Lipid-decreasing therapy as essential component in treatment and prophylaxis of cardiovascular diseases. Rus Med Zhurnal 2011;19 (7): 450–454.

Klimov A.N., Nikulcheva N.G. Exchange of lipids and lipoproteids and its disorder. St. Petersburg: Piter Kom, 1999.

Morozova R.P., Kozulina E.P., Nikolenko I.A. et al. Placenta as source of biologically active substances. Ukr Biokhim Zhurnal 1999; 71 (4): 21–29.

Moshko Yu.A. Application of cryopreserved cord blood serum in treatment of women with chronic salpingoophorites. Problems of Cryobiology 2001; (1): 70–75.

Placenta: cryopreservation, structure, properties and perspectives of clinical application. Ed. by V.I. Grischenko, T.N. Yurchenko Kharkov, 2011.

Romantsova T.I., Kurlyandskaya R.M. Role of growth hormone in regulation of fat and carbohydrate metabolism. Lechaschy Vrach 2002; (5): 36–38.

Sayuk Yu.M., Chepil I.V., Kravchuk M.E. et al. Experience of complex treatment of patients with acute pancreatitis. Shpytalna Khirurgiya 2004; (4): 172–175.

Stefanov O.V. Preclinical studies of preparations Kyiv: Avitsena, 2001.

Strona V.I., Stepanov A.V., Prokopyuk O.S. Plasmapheresis and implantation of placental tissue in complex treatment of atherosclerosis in patients with ischemic heart disease. Meditsyna Segodnya i Zavtra 1997; (2): 54–55.

Sumin A.N., Gayfulin R.A., Bezdenezhnykh A.V. et al. Occurrence of multifocal atherosclerosis in different age groups. Kardiologiya 2012; 52 (6): 28–34.

Falko O.V. Application of human placental blood serum as perspective method to correct atherosclerotic changes (experimental studies). Problems of Cryobiology 2012; 22 (2): 133–143.

Khmelnitsky O.K., Stupina A.S. Functional morphology of endo-crine system at atherosclerosis and ageing. St. Petersburg, 1989.

Shyrshev S.V. Immunology of maternal-fetal interrelations Ekaterinburg: Ural Branch of the Russian Academy of Sciences, 2009.

Patent N42454. Ukraine. Biostimulating preparation ‘Cryo-cord-C’ and method for treatment of chronic salpingoophorites with its application. V.I. Grischenko, O.V. Lipina, O.S. Prokopyuk, Yu.O. Moshko. Appl. 05.03.2001. Publ. 15.12.2004. Bul. N12.

Cagnacci A., Cannoletta M., Caretto S. еt al. Increased cortisol level: a possible link between climacteric symptoms and cardio–vascular risk factors. Menopause – 2011; 18 (3): 273–278.

Dekker M.J., Koper J.W., Aken M.O. et al. Salivary cortisol is related to atherosclerosis of carotid arteries. J Clin Endocrinol Metab 2008; 3 (10): 3741–3747.

DeSantis A.S., DiezRoux A.V., Hajat A. et al. Associations of salivary cortisol levels with metabolic syndrome and its components: the multi–ethnic study of atherosclerosis. J Clin Endocrinol Metab 2011; 6 (11): 3483–3492.

Do D.P., DiezRoux A.V., Hajat A. et al. Circadian rhythm of cortisol and neighborhood characteristics in a population-based sample: the multi–ethnic study of atherosclerosis. Health Place 2011; 17 (2): 625–632.

Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of plasma low density lipoprotein cholesterol concentration with use of the preparative ultracentrifuge. Clin. Chem 1972; 18 (6): 499–502.

Downloads

Published

2013-03-15

How to Cite

Falko, O. V., Prokopyuk, O. S., Volina, V. V., & Lipina, O. V. (2013). Application of Placental Blood Serum to Correct Disordered Morphofunctional State of Adrenal Glands at Experimental Atherosclerosis. Problems of Cryobiology and Cryomedicine, 22(1), 75–83. Retrieved from https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/13

Issue

Section

Cryomedicine, Clinical and Experimental Transplantology