On the Modification of Immunoreactivity of Myelotransplant after Cryopreservation

Authors

  • A. N. Goltsev Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • I. Yu. Matsevitaya Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Ye. D. Lutsenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • M. V. Ostankov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. G. Dubrava Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • K. A. Goltsev Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Ye. Ye. Yampolskaya Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

bone marrow adhesive cells, cryopreservation, myelotransplant immunoreactivity

Abstract

The comparative analysis of structure-functional characteristics of bone marrow adhesive cells (BMACs) prior to and after cryopreservation was carried out. The data obtained confirm importance of BMACs as a component of myelotransplant with antigenpresenting function in the general mechanism of T-cell activation that induce graft-versus-host reaction (GVHR). The results allow to understand the mechanisms of immune interactions between cryopreserved allomyelotransplant and the recipient's organism and opportunities of applying the cryopreservation of bone marrow for minimization of GVHR.

Downloads

Published

2010-06-07

How to Cite

Goltsev, A. N., Matsevitaya, I. Y., Lutsenko, Y. D., Ostankov, M. V., Dubrava, T. G., Goltsev, K. A., & Yampolskaya, Y. Y. (2010). On the Modification of Immunoreactivity of Myelotransplant after Cryopreservation. Problems of Cryobiology and Cryomedicine, 20(2), 145–152. Retrieved from https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/203

Issue

Vol. 20 No. 2 (2010): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 A. N. Goltsev, I. Yu. Matsevitaya, Ye. D. Lutsenko, M. V. Ostankov, T. G. Dubrava, K. A. Goltsev, Ye. Ye. Yampolskaya

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).