Effect of Cryopreserved Bone Marrow Transplantation on Dynamics of Recovery of Morphofunctional Properties of Lymphoid, Myeloid and Endocrine Organs in Lethally Irradiated Recipients

Authors

  • A. A. Tsutsayeva Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • S. S. Chernousova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. A. Glushko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. E. Shatilova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • V. V. Volina Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. V. Sokol Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. Yu. Ivakhnenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. G. Chernyshenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • E. V. Brovko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

lethal irradiation, transplantation, cryopreserved syngeneic bone marrow, lymphoid organs, myeloid organs, endocrine organs, hormones

Abstract

There was realised a combined study of morphofunctional properties of lymphoid, myeloid and endocrine organs in lethally irradiated mice at different stages after cryopreserved syngeneic bone marrow (CSBM) cell transplantation. The CSBM cell transplantation to lethally irradiated animals demonstrated the stimulation of recovery processes in neurohumoral organs. At the same time the wave-like changes in triiodothyronine (T3), thyroxin (T4), corticosterone and insulin hormone levels in peripheral blood, even if not reaching the level of physiological norm, provide the survival within 3 months for lethally irradiated animals, dying without transplantation to the 10th day.

Downloads

Published

2009-05-25

How to Cite

Tsutsayeva, A. A., Chernousova, S. S., Glushko, T. A., Shatilova, L. E., Volina, V. V., Sokol, L. V., Ivakhnenko, L. Y., Chernyshenko, L. G., & Brovko, E. V. (2009). Effect of Cryopreserved Bone Marrow Transplantation on Dynamics of Recovery of Morphofunctional Properties of Lymphoid, Myeloid and Endocrine Organs in Lethally Irradiated Recipients. Problems of Cryobiology and Cryomedicine, 19(1), 71–87. Retrieved from https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/289

Issue

Vol. 19 No. 1 (2009): Problems of Cryobiology

Section

Cryomedicine, Clinical and Experimental Transplantology

License

Copyright (c) 2020 A. A. Tsutsayeva, S. S. Chernousova, T. A. Glushko, L. E. Shatilova, V. V. Volina, L. V. Sokol, L. Yu. Ivakhnenko, L. G. Chernyshenko, E. V. Brovko

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).