Comparative Characteristics of Cardiac Rate in Rats When Applying Different Methods of Cold Effects

Authors

  • V. G. Babijchuk Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

rhythmic cryotherapy, blood brain barrier, cardiac rate, pinocytosis, horse radish peroxidase

Abstract

Comparative characteristics of cardiac rate in rats of different age groups, cooled by both methods of standard extreme cryotherapy and rhythmic one, proposed by the author, have been presented. Negative chronotropic effect after norepinephrine intraperitoneal introduction into rats is observed only after the 9th cooling session by the standard method and after the 3rd one if cooling with the rhythmic effects, that might testify to earlier terms of blood brain barrier (BBB) permeability for neuromediator. This may be confirmed by pinocytosis activation in capillary endotheliocytes, as well as by revealing the horse radish peroxidase granules in endotheliocyte fragments of cerebral capillary.

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Published

2007-10-25

How to Cite

Babijchuk, V. G. (2007). Comparative Characteristics of Cardiac Rate in Rats When Applying Different Methods of Cold Effects. Problems of Cryobiology and Cryomedicine, 17(3), 229–236. Retrieved from https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/493

Issue

Vol. 17 No. 3 (2007): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 V. G. Babijchuk

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