Age Peculiarities of Nitrogen Oxide Role in Adaptation Mechanisms of Animals to Rhythmic Cold Effects. Report 1. Content of Final Products of NO Exchange in Blood and Myocardium of Young and Aged Animals after Rhythmic Cold Effects

Authors

  • V. G. Babijchuk Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

rhythmical cold effects, nitrogen oxide, nitrites, blood serum, myocardium, NO-synthase

Abstract

Influence of rhythmical cold effects (–120°C) on content of final products of nitrogen oxide (NO) exchange in blood serum and myocardium of young and aged rats has been studied. NO activity is supposed to play a role of pathogenic regulatory factor, whose activity is reduced in aged rats. The rise in the content of NO exchange final products in blood serum after 6 sessions of extreme cryoeffects in young rats and after 6-9 sessions in aged ones has been noted. The reduction of the content of nitrites in myocardium of rats can indicate an NO intensive expenditure by myocardial cells. The similar effect for aged rats in the dynamics of experiment is “delayedâ€, that is related to a decline in adaptive possibilities of ageing organism.

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Published

2006-12-15

How to Cite

Babijchuk, V. G. (2006). Age Peculiarities of Nitrogen Oxide Role in Adaptation Mechanisms of Animals to Rhythmic Cold Effects. Report 1. Content of Final Products of NO Exchange in Blood and Myocardium of Young and Aged Animals after Rhythmic Cold Effects. Problems of Cryobiology and Cryomedicine, 16(4), 377–389. Retrieved from https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/572

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Section

Theoretical and Experimental Cryobiology