Some Indices of Erythropoiesis System of Rats after Partial Hepatectomy and Transplantation of Cryopreserved Embryonic Liver Cells

Authors

  • N. N. Moiseyeva Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv
  • E. D. Rozanova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv
  • S. P. Mazur Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv
  • A. Yu. Petrenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

Abstract

The authors studied the content of fetal and total hemoglobin in blood of rats after 70%-hepatectomy and transplantation of cryopreserved human embryonic liver (HEL) cells. Partial hepatectomy leads to a decrease in the content of total hemoglobin in rats’ blood during experiment and increasing of fetal hemoglobin level by the 3rd day. After transplantation of cryopreserved HEL cells the content of total hemoglobin markedly exceeds the results in partially hepatectomised rats without transplantation by the 1st and 2nd day, and the level of fetal hemoglobin during this period decreased in 1.5 times. The transplant was identified in histological sections of liver and spleen from partially hepatoectomised rats with the method of fluorescent microscopy using  monoclonal antibodies, labelled with fluorescent dye CD45-FITC.

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Published

2002-12-25

How to Cite

Moiseyeva, N. N., Rozanova, E. D., Mazur, S. P., & Petrenko, A. Y. (2002). Some Indices of Erythropoiesis System of Rats after Partial Hepatectomy and Transplantation of Cryopreserved Embryonic Liver Cells. Problems of Cryobiology and Cryomedicine, (4), 72–75. Retrieved from https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/992

Issue

No. 4 (2002): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 N. N. Moiseyeva, E. D. Rozanova, S. P. Mazur, A. Yu. Petrenko

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