TY - JOUR AU - Aminov , Ruslan AU - Frolov, Оleksandr AU - Aminova, Alina AU - Makyeyeva , Lyudmyla PY - 2022/10/30 Y2 - 2024/03/28 TI - Evaluation of Mitotic Activity of Bone Marrow Under Short-Term Hypothermia JF - Problems of Cryobiology and Cryomedicine JA - Probl Cryobiol Cryomed VL - 32 IS - 2 SE - Theoretical and Experimental Cryobiology DO - 10.15407/cryo32.02.081 UR - https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/1789 SP - 81-91 AB - <p>In this research, we have studied the mitotic activity of bone marrow when applying medicinal leeches and short-term hypothermia. The bone marrow mitotic indices were compared within an immediate examination of the thigh removed from the body and during a short-term hypothermia. As a result, no statistical differences were found between the mitotic levels during immediate examination and a short-term hypothermia in the intact animals and those after medicinal leech application, that evidenced to a hypothermal fixation of initial level of this index, preservation of biomembrane physiological state prior to hypotonic stress and cell morphology. The used here short-term hypothermia on bone marrow cells may be included in the multi-profile algorithm of laboratory analysis when studying a mitotic index in actively proliferating cells.</p><p>&nbsp;</p><p><em>Probl Cryobiol Cryomed 2022; 32(2):</em><em>081</em><em>–</em><em>091</em></p> ER -