Effect of Cryopreserved Culture of Pancreas Microfragments on Immune Status of Rats with Aloxane Diabetes Development

Authors

  • L. V. Ostankova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • O. N. Pobelensky Kharkov National University, Kharkov
  • M. V. Ostankov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • A. N. Goltsev Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

cryopreserved culture, pancreas, immune status, aloxane diabetes model

Abstract

The effect of cryopreserved culture of newborn piglet pancreas microfragments on rat’s immune status in the model of aloxane diabetes (AD), similar to human insulin-dependent diabetes mellitus has been studied. Administration of pancreas microfragment cryopreserved culture was demonstrated as contributing to cell and humoral immunity link recovery. The most manifested effect was after its introduction into parapancreatic fat.

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Published

2006-09-15

How to Cite

Ostankova, L. V., Pobelensky, O. N., Ostankov, M. V., & Goltsev, A. N. (2006). Effect of Cryopreserved Culture of Pancreas Microfragments on Immune Status of Rats with Aloxane Diabetes Development. Problems of Cryobiology and Cryomedicine, 16(3), 316–325. Retrieved from http://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/587

Issue

Section

Cryomedicine, Clinical and Experimental Transplantology