Study on the dependence of alpha-fetoprotein content in human cord blood extracts on extraction conditions

Authors

DOI:

https://doi.org/10.15407/cryo35.04.226

Keywords:

cord blood, alpha-fetoprotein, cryodestruction, biologically active substances, cryoextract

Abstract

Probl Cryobiol Cryomed. 2025; 35(4): 224—226

Author Biographies

Ivan I. Shcheniavskyi, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

Department of Cold Adaptation

Yuliia S. Akhatova, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

Department of Cold Adaptation

Natalia M. Moisieieva, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

Department of Cold Adaptation

Olga L. Gorina, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

Department of Cold Adaptation

References

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Bogdanov AYu, Bogdanova TM, Ilin AI. Endocytic pathway of alpha-fetoprotein in mice bone marrow hematopoietic stem cells: molecular characterization and role in biological activity modifi cation. Cytol Genet. 2014; 48: 21-32. CrossRef

Dudich E. MM-093, a recombinant human alpha-fetoprotein for the potential treatment of rheumatoid arthritis and other autoimmune diseases. Curr Opin Mol Ther. 2007; 9(6): 603-10. PubMed

Fahy GM, Wowk B. Principles of ice-free cryopreservation by vitrification. Methods Mol Biol. 2021; 2180: 27-97. CrossRef

Głowska-Ciemny J, Szymański M, Kuszerska A, et al. The role of alpha-fetoprotein (AFP) in contemporary oncology: the path from a diagnostic biomarker to an anticancer drug. Int J MolSci [Internet]. 2023 Jan 28 [cited 2025 Feb 04]; 24(3):2539. Available from: https://www.mdpi.com/1422-0067/24/3/2539 CrossRef

Gulevskyy AK, Akhatova YuS. Current concept to the structural and functional properties of alfa-fetoprotein and the possibilities of its clinical application. Biotechnologia Acta. 2021;14(1): 25-37. CrossRef

Lin B, Liu K, Wang W, et al. Expression and bioactivity of human α-fetoprotein in a Bac-to-Bac system. Biosci Rep [Internet]. 2017 Jan 17 [cited 2025 Feb 06]; 37(1): BSR20160161. Available from: https://portlandpress.com/bioscirep/article/37/1/BSR20160161/56527/Expression-and-bioactivity-of-human-fetoprotein-in CrossRef

Mizejewski GJ. Alpha-fetoprotein structure and function: relevance to isoforms, epitopes, and conformational variants. Exp Biol Med. 2001; 226: 377-408. CrossRef

Mizejewski GJ. Alpha-fetoprotein: Immunomodulation in autoimmune diseases during pregnancy and puerperium stages. GSC Biol Pharm Sci. 2022; 20(02): 102-13. CrossRef

Munson PV, Adamik J, Butterfi eld LH. Immunomodulatory impact of α-fetoprotein. Trends Immunol. 2022; 43(6): 438-48. CrossRef

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Published

2026-03-08

How to Cite

Shcheniavskyi, I., Akhatova, Y., Moisieieva, N., Gorina, O., & Lipko, O. (2026). Study on the dependence of alpha-fetoprotein content in human cord blood extracts on extraction conditions. Problems of Cryobiology and Cryomedicine, 35(4), 226—228. https://doi.org/10.15407/cryo35.04.226

Issue

Vol. 35 No. 4 (2025): Probl Cryobiol Cryomed

Section

Short communications

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