Obstetric and Perinatal Outcomes of Pregnancies After Infertility Treatment Using Assisted Reproductive Technologies With Cryopreserved Embryo Transfer
DOI:
https://doi.org/10.15407/cryo28.03.249Keywords:
cryopreservation, vitrification, obstetric outcome, perinatal outcome, assisted reproductive technologiesAbstract
The paper presents an analysis of the data on obstetric and perinatal outcomes of pregnancies after infertility treatment by the methods of assisted reproductive technologies (ART) using the transfer of one selected cryopreserved embryo, particularly the outcomes of spontaneous and induced singleton pregnancies. The clinical and anamnestic data of patients were analyzed. The course of pregnancy, childbirth and the state of the newborn were assessed using the data of individual medical record of the pregnant woman and discharge report from the maternity hospital. The criteria for assessing obstetric and perinatal outcomes included: the frequency of normal physiological and preterm delivery, the method of delivery and the weight of children at birth. Factors influencing the course of pregnancy and the condition of children born after natural conception and the use of ART have been determined. It was found that in a group of patients with transfer of a cryopreserved embryo of delivery by cesarean section are performed more often. The body mass index of newborns was statistically and significantly higher than in the groups with spontaneous and induced pregnancies: (3,653.3 ± 550.5) (3,420.2± 547.1) and (3,087.1 ± 704.7) g, respectively.
Â
Probl Cryobiol Cryomed 2018; 28(3): 249–257
References
Belva F, Henriet S, Van den Abbeel E, et al. Neonatal outcome of 937 children born after transfer of cryopreserved embryos obtained by ICSI and IVF and comparison with outcome data of fresh ICSI and IVF cycles. Hum Reprod. 2008;23(10): 2227‒38. CrossRef PubMed
Boychuk OG, Makarchuk OM. [The problem of infertility in Ukraine: the role of auxiliary reproductive technologies (ART) and the course of pregnancy in women with long-term infertility]. Arkhiv Klinichnoi Medytsyny. 2010; 1: 4‒8. Ukrainian.
De los Santos MJ, Apter S, Coticchio G, et al. Revised guidelines for good practice in IVF laboratories (2015). ESHRE Guideline Group on Good Practice in IVF Labs. Hum Reprod. 2016; 31(4):685‒6. CrossRef PubMed
El-Toukhy T, Kamal A, Wharf E, et al. Reduction of the multiple pregnancy rate in a preimplantation genetic diagnosis programme after introduction of single blastocyst transfer and cryopreservation of blastocysts biopsied on day 3. HumReprod. 2009; 24(10):2642‒8. CrossRef PubMed
Grischenko VI, Gerodes AG, Petrushko MP, Pinyaev VI. [Use of human follicular fluid at the stage of cultivation of gametes and embryos in the IVF program]. Problemy Reproduktsii. 1999; 5(7):34‒37. Russian.
Grishchenko VI, Petrushko MP, Pinyaev VI. [Effectiveness of the IVF program, depending on the number and quality of the embryos transferred]. Problemy Reproduktsii. 2000; 6(1): 44‒7. Russian.
Kuwayama M. Highly efficient vitrification for cryopreservation of human oocytes and embryos: the Cryotop Method. Theriogenology. 2007; 67(1):73‒80. CrossRef PubMed
Li Z, Wang YA, Ledger W, Edgar DH, et al. Clinical outcomes following cryopreservation of blastocysts by vitrification or slow freezing: a population-based cohort study. Hum Reprod. 2014; 29(12):2794‒801. CrossRef PubMed
Maas K, Galkina E, Thornton K. No change in live birthweight of IVF singleton deliveries over an 18-year period despite significant clinical and laboratory changes. Hum Reprod. 2016; 31(9):987–96. CrossRef PubMed
Morozov V, Ruman J, Kenigsberg D, et al. Natural cycle cryo-thaw transfer may improve pregnancy outcome. J Assist Reprod Genet. 2007; 24(3):119‒23. CrossRef PubMed
Pelkonen S, Koivunen R, Gissler M, et al. Perinatal outcome of children born after frozen and fresh embryo transfer: theFinnish cohort study 1995–2006. Hum Reprod. 2010; 25(4): 914–23. CrossRef PubMed
Pelkonen S, Gissler M, Koivurova S, et al. Physical health of singleton children born after frozen embryo transfer using slow freezing: a 3-year follow-up study. Hum Reprod. 2015; 30(10): 2411‒8. CrossRef PubMed
Petrushko MP. [Current state of the problem of cryopreservation of reproductive cells and human embryos]. Visnyk Nac Acad Nauk Ukr. 2017; (7): 44‒52. Ukrainian.
Petrushko MP. Use of cryopreserved human embryos in assisted reproductive technologies. Problems of Cryobiology. 2000; 10(1):171‒5. Full Text
Takahashi K, Mukaida T, Goto T, et al. Perinatal outcome of blastocyst transfer with vitrification using cryoloop: a 4-year follow-up study. Fertil Steril. 2005; 84(1):88–92. CrossRef PubMed
Yurchuk TA, Petrushko MP, Pinyaev VI. Efficiency of cryopreservation of expanded blastocysts by the method of vitrification using collapsing. Probl Cryobiol Cryomed. 2016; 26(2): 167. CrossRef
Zabolotko VM. [Information and statistical guide about assisted reproductive technologies in Ukraine]. Kyiv: 2017: 28 p. Ukrainian.
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
