Phase transformation and protein-hormonal profile of human cord blood serum at low temperatures

Authors

Keywords:

сord blood serum, thermomechanical analysis, low temperatures, cryopreservation, lyophilization, growth factors, hormones

Abstract

Probl Cryobiol Cryomed. 2026; 36(2): 139—142

 

Author Biographies

Dmytro O. Salnykov, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine

Department of Cold Adaptation

Anastasiia A. Skoryk, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine

Department of Cold Adaptation

Hanna L. Poliakova, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine

Department of Low Temperature Preservation

Tetiana M. Gurina, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine

Department of Low Temperature Preservation

Mariia V. Shevchenko, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine

Department of Cold Adaptation

Olga S. Prokopiuk, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine

Department of Cold Adaptation

References

Ehrhart J, Sanberg PR, Garbuzova-Davis S. Plasma derived from human umbilical cord blood: Potential cell-additive or cell-substitute therapeutic for neurodegenerative diseases. J Cell Mol Med. 2018; 22(12): 6157-66. CrossRef

James J. Thermomechanical analysis and its applications. In: Thomas S, Thomas R, Zachariah AK, Mishra RK, editors. Thermal and rheological measurement techniques for nanomaterials characterization. Amsterdam: Elsevier; 2017. p. 159-71. CrossRef

Kaverinska A, Prokopiuk V. Comparison of the effects of umbilical cord cryoextract and lyophilized form on the adhesive, proliferative, and metabolic properties of various cell types. The Journal of V.N.Karazin Kharkiv National University. Series Biology. 2024; 43: 96-104. CrossRef

Maharajan N, Cho GW, Choi JH, Jang CH. Regenerative therapy using umbilical cord serum. In Vivo. 2021; 35(2): 699-705. CrossRef

Moghassemi S, Nikanfar S, Dadashzadeh A, et al. The revolutionary role of placental derivatives in biomedical research. Bioact Mater. 2025; 49: 456-85. CrossRef

Pakhomov O, Gurina T, Mazaeva V, et al. Phase transitions and mechanisms of cryoprotection of serum-/xeno-free media based on dextran and dimethyl sulfoxide. Cryobiology. 2022; 107: 13-22. CrossRef

Pakhomov O, Gurina T, Polyakova A, et al. Study of physical processes occurring in serum-containing and polymer-based serum-free cryoprotective media. Biopolym Cell. 2024; 40(1): 37-46. CrossRef

Prokopyuk OS, Lipina OV, Grishchenko VI, inventors; Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, assignee. Method for obtaining lyophilized human cord blood serum. Patent of Ukraine No. 26543. 2007 Sep 25.

Prokopyuk V, Karpenko V, Shevchenko M, et al. Experience in clinical application of cryopreserved placental derivatives: cells, tissue, membranes, extract, and cord blood serum. Innovative Biosystems and Bioengineering. 2020; 4(3): 168-76. CrossRef

Shevchenko M, Skoryk A, Salnykov D, et al. Preservation of protein fractions and hormones of placental blood serum after freeze-drying. Probl Cryobiol Cryomed. 2026; 36(1): 58-65. CrossRef

Published

2026-07-14

How to Cite

Salnykov, D., Skoryk, A., Poliakova, H., Gurina, T., Shevchenko, M., Lipko, O., & Prokopiuk, O. (2026). Phase transformation and protein-hormonal profile of human cord blood serum at low temperatures. Problems of Cryobiology and Cryomedicine, 36(2), 139—142. Retrieved from https://journal.cryo.org.ua/index.php/probl-cryobiol-cryomed/article/view/2198

Issue

Section

Short communications