Effect of Trifluoperazine and Dodecyl-β,D-maltoside on Hypertonic Stress of Mammalian Erythrocytes
DOI:
https://doi.org/10.15407/cryo24.03.231Keywords:
mammalian erythrocytes, hypertonic stress, amphiphilic compounds, potassium cationsAbstract
The effect of dodecyl-β,D-maltoside (DM) and trifluoperazine (TFP) on mammalian (human, bovine, equine, rabbit)
erythrocyte sensitivity to hypertonic stress (HS) (4.0 mol/l NaCl) was studied in this work. The use of amphiphilic compounds in the certain concentrations was demonstrated as resulting in an increased resistance to HS of human, bovine, equine erythrocytes, but not rabbit ones. Protective effect of amphiphilic compounds is higher at 37°C than at 0°C. Cationic TFP is more efficient than non-ionic DM. The substances under study were established as not affecting the potassium cation release out of cells under HS. Protective mechanism of TFP and DM is suggested as associated with their perturbating action on a membrane and prevention of transmembrane defect development up to hemolytic pore size.
Probl Cryobiol Cryomed 2014; 24(3):231-237.
References
Balgavy P., Devinsky F. Cut-off effects in biological activities of surfactants. Adv Colloid Interface Sci 1996; 66: 23–63. CrossRef
Belous A.M., Gordienko E.A., Rozanov L.F. Freezing and cryoprotection. Moscow: Vyscha Shkola; 1987.
Belous A.M., Grischenko V.I. Cryobiology. Kiev: Nauk Dumka; 1994.
Ferlazzo A.M., Bruschetta G., Di Pietro P. et al. Phospholipid composition of plasma and erythrocyte membranes in animal species by 31P NMR. Vet Res Commun 2011; 35: 521–530. CrossRef PubMed
Fuller B.J., Lane N., Benson E.E., editors. Life in the frozen state. Boca Raton: CRC Press; 2004.
Gordienko E.A., Pushkar N.S. Physical grounds of low temperature preservation of cell suspensions. Kiev: Nauk Dumka; 1994.
Gulevsky A.K., Bondarenko V.A., Belous A.M. Barrier properties of biomembranes at low temperatures. Kiev: Nauk Dumka; 1988.
Hagerstrand H., Isomаa B. Amphiphile-induced antihaemolysis is not causally related to shape changes and vesiculation. Chem Biol Inter 1991; 79: 335–347. CrossRef
Hanpft R., Mohr K. Influence of cationic amphiphilic drugs on the phase-transition temperature of phospholipids with different polar headgroups. Biochim Biophys Acta 1985; 814(1): 156–162. CrossRef
Kanaho Y., Sato T., Fujii T. The affinity of various phenothiazine drugs for membranes of intact erythrocytes and their membrane-transforming activity. Mol Pharmacol 1981; 20: 704–708.
Malheiros S.V., Brito M.A., Brites D., Meirelles N.C. Membrane effects of trifluoperazine, dibucaine and praziquantel on human erythrocytes. Chem Biol Inter 2000; 126: 79–95. CrossRef
Nelson G.J. Composition of neutral lipids from erythrocytes of common mammals. J Lipid Research 1967; 8(4): 374–379.
Orlova N.V., Shpakova N.M. Mechanism of protective effect of amphiphilic compounds under hypertonic hemolysis of erythrocytes. Fiziol Zhurnal 2006; 52(5): 55–61.
Schreier S., Malheiros S.V., Paula E.D. Surface active drugs: self-association and interaction with membranes and surfactant. Physicochemical and biological aspect. Biochim Biophys Acta 2000; 1508(1–2): 210–234.
Shpakova N.M. Possible mechanism of correction of osmotic and temperature sensitivity of human erythrocytes using alkyl-b,D-glucopyranosides. Problems of Cryobiology 2009; 19(4): 449–460.
Shpakova N.M., Dunayevskaya O.N., Synchikova O.P. Effect of trifluoperazine on erythrocyte hemolysis in hypertonic solutions of electrolytes. Problems of Cryobiology 2002; 3: 7–15.
Shpakova N.M., Pisarenko N.A., Nipot E.E. Effect of alkyl sulfates on hypertonic hemolysis of mammalian erythrocytes. Problemy Zooinzhenerii ta Veterinarnoi Meditsyny 2010; 2 (21 Pt 2): 89–96.
Tsymbal L.V., Orlova N.V., Shpakova N.M. Modification with chlorpromazine of structural and functional state of erythrocyte membranes. Biol Membrany 2005; 22(4): 327–335.
Wessels J.M., Veerkamp J.H. Some aspects of the osmotic lysis of erythrocytes III. Comparison of glycerol permeability and lipid composition of red blood cell membranes from eight mammalian species. Biochim Biophys Acta 1973; 291(1): 190–196. CrossRef
Yawata Y. Cell membrane: the red blood cell as a model. Weinheim: Wiley-VCH Verlag; 2003.
Yershova N.A., Shpakova N.M., Orlova N.V. Effect of phenyl-hydrazine and alkyl sulfates on osmotic sensitivity of mammalian erythrocytes. Reports of Nat Acad Sci of Ukraine 2012; 6: 129–133.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Natalia A. Yershova, Elena E. Nipot, Natalia M. Shpakova, Sergey S. Yershov, Natalia V. Orlova
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
